... La tarjeta gfx no debería ser realmente un problema (¿pero podría ser con Renoise?)
This makes one wonder. We all know that resolutions 4K or higher are not the ideal scenario for Renoise 3, in the absence of an important update of the GUI, as marked "a possible roadmap future".
Therefore, Renoise may not be highly optimized for certain GPU models that are not very powerful along with high resolutions, 4K or higher... I'm almost convinced that with a more powerful PC (dedicated PCIe sound card and dedicated PCIe graphics card), I should not have any problems at 4K.
Have you tried doing a neat reinstallation of Renoise? For that you have to make sure to remove any traces of the previous installation...
As they told me a long time ago, Renoise prioritizes the audio before the GUI so the audio always should sounds good, even though the GUI shows "slight delays" when playing the song. When there are audio cuts, it seems reasonable to think that it is not able to support both scenarios, the prioritization of audio along with playback in the GUI (and this is due to poorly optimized drivers or to the hardware itself, or the optimization of Renoise or even Windows 10 (do not stop having updates, for something will be)). This seems to translate into a hardware problem, probably performance, unbalanced PC to run Renoise in 4K or driver problems/bad installation or even configuration. Then, it is possible that Studio One works well, since it is more optimized for these resolutions with less powerful hardware and have correct all software installation and drivers.
Having said all these thoughts, it seems reasonable, if is possible, to try changing the hardware to see if it works better or not. I doubt there is any user currently using Renoise + 4K or higher that can help here, unfortunately.
It would also be reasonable for you to specify your main hardware:
- Desktop or laptop pc?
- sound card (integrated, USB, PCIe??)
- model of monitor (features?)
Maybe with more data from your hardware, people know how better to help you...