I know it should work somehow, yet still seeing Win7 in the official #specs.
We also mention Windows Vista there, so you can probably guess that we haven't really updated the minimum requirements text in quite some time
I've been running Windows 10 at home for a couple of years now, and taktik has also been running Windows 10 at the office for quite some time.
I also have a second machine that was originally running Windows 7, which I then upgraded to Windows 8, and then finally to Windows 10.
I personally haven't experienced any major problems so far, and Renoise is running quite happily on both of my systems.
Your experience may of course vary, especially if your audio interface is lacking the proper up to date drivers.