try running Renoise as administrator. people have reported this issue quite often in the past. It turned out to be a bug into the VST, but since in Windows 7 it is working, it could be an user priviledge issue
I quit using edirol for the same reason, it never saved my settings…no matter what DAW I was using. These days you’re probably better off using kontakt sample libraries though, the sound quality of edirol seems a bit dated.