Guitar Amp Modellers / Pod X3

I would recommend getting the free version of Studio Devils virtual amp before you look much further.

If you like the sound you can get the full version for 79$, which is a decent price at any rate, and it got a 10/10 in Computer Music.

It feels, and plays, quite like an actual amp - not too many bells and whistles.
I never got comfy with multieffects in a guitar setting, it always felt more natural to lug the combo and the bag of stomp boxes around, so this amp has a very familiar feel to it.