I’m not sure, if this is a bug or just the current way how pitch shifting / time stretching is working inside Renoise. I’ve attached a demo song with one pad sample and a cheesy little melody and it takes up 70% cpu usage on my i7 3770k. Maybe it’s possible to optimize it more
Edit: Ok, it seems lowering the beat sync pattern lines amount also reduce the cpu usage dramatically. So its currently not a good idea to stretch long samples to short ones.