NOte off , just a matter of replacing the font?

Is it possible to replace the " OFF" word with just a symbol , or would each letter has to be replaced ?
1
Photoshop mock-up

Unlikely that this is supported in the text rendering in Renoise but you can try via the ligature feature of fonts, which allows modern text renderers to merge stuff like -> into →

You can of course replace the individual letter but that will mess up F in other places as well.