Those Native Effects That I Never Understood...

-lo-fi mat (‘it rocks’, says the tip of the day!)
-disto and scream filters : awfully destructive effect, sometimes i use disto on the slightest settings possible, but not more!
-comb filter
-ringmod

I use all of these all the time except for the scream filter.

I use lo-fi to dirty up drums and bass.
I use distortion on almost everything.
The comb filter is great for higher drums and pads if you hook it up to an lfo.
Ditto for the ring mod.

I don’t think I’ve ever used the scream filter. I’ve tried, but I just don’t like the way it sounds.