Vst's Randomly Losing Sound

Upon reloading a file sometimes a soft synth or two that played when I saved it, will make no sound.
I have to change the preset on the synth and back again to get it to make a sound. It represents an inconvenience in that with more textural passages, it will not be immediately apparent exactly what is missing, but it will be obvious that something sounds unpleasantly different.
It’s a pain to hunt down.

Anyone else encountered this?

i havent have completly missing sound but rather “different sound” or default preset or something… But i think that its more of those vsts fault than renoises.