About audio of Renoise preference

16 bit signed, 16 bit unsigned here
32 bit signed int, 32 bit unsigned int

What’s the difference?
Also does it have a change in sound?

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this is not specific to Renoise, this is audio topic in general. Google is your friend:
https://groups.google.com/g/comp.games.development.audio/c/d6oSAppZm6M?pli=1

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Thank you!

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