Hi Emmanuel,
generally speaking, support for the Quneo is still quite rudimentary, but you should be able to make many interesting configurations for it(mixer, sequencers, drumpads). See also the Quneo/Duplex discussion located here.
first duplex can send midi to the Quneo but the Quneo cannot send midi to duplex
Can you see if Renoise receives any MIDI from the Quneo (the MIDI tab in Renoise should list all messages) ?
Also, the Quneo configuration that Duplex comes with assumes that the Quneo is configured in a special way - you might want to either change how the Quneo transmit messages (it comes with a utility to do this), or change the Duplex control-map for Quneo
second how can i configure the Quneo in duplex
Satobox has written a nice introduction to this, located here.
Quneo is a complex controller so don’t be afraid to ask questions.