Yes, I’m using VSTs and no samples, VST effects too, Renoise 3.3.2, Win10 64bit updated, i7 8700K, 32 GB ram, many drives, nice PC case, 27" monitor, GeForce 1660 Super…
From my experience any details like that never solve any problem. And how can they? If you never have problem like that then no matter what version of Windows I have, it doesn’t help you to figure out where the problem is. The same about VSTs (if you knew that some particular vst could be causing this, you would definitely share that knowledge). The same about system etc.
Don’t let me wrong, but I spend lot of time on computer related forums and saw thousands of questions like that (asking for detailed configuration) and never seen any post where it helps. I was counting more on that someone (programmer who work on Renoise) will look at part of code that may cause this problem in theory and make some tests or improvements (or at least debug version that generate log if output of mix contains zeros). It’s probably related to VSTs, but who knows which ones. Problem is that if I run render second time - everything works. And funny thing is that NOTHING is rendered, even if I use 20 tracks with different VST instruments used. Because problem is hard to reproduce, the only way to figure out what is wrong is to look at code and figure out what can cause this problem. It would have to be done anyway even if I had found specific VST.
I really liked my 3.2.1 version, but unfortunately I need VST3 now.