I was using elastique pitch v2 on a sample inside the effect chains. After adding it other samples using phrases (like sliced up drum breaks) were’nt played correctly. There was a short gap of silence at the end of the phrase loop. Could be possible, that this gap of silence was exactly the length of the latency of elastique pitch v2. It seems its currently not a good idea to use vst effects with big latency in effect chains.
Renoise 64bit 3.1.1, Windows 10, DirectSound