Greetings to Renoise team!
Here’s one basic advice of mine (if I may say so): Never ever remove anything which already exists and works from the program! You might try organizing it differently, you might try temporally disabling it (depending on the circumstance), you might try furthering it, or you might try putting it elsewhere. But just deleting or erasing or removing anything that works (no matter what future concept) is never necessary and always harmful! That refers to virtually anything: from instruments to songs to fine-loop editors to themes. Anything!