Anyone know how to those high pitched hiphop leads, like dr dre always uses, can you do stuff like this in renoise and also can you do those detuned pianos also like aphex twin uses ect? I think it’s something to do with the glide of the notes but is it possible in Renoise 
To make a Druqks style detuned piano you’d need to get a real piano and stick nuts and bolts and shit inbetween the strings like John Cage.
As for the leads, that type of stuff just sounds like a sine wave gliding between the notes, use a VST synth like Voyager or do it all in renoise with ‘glide to note’.
Step 1: Grab the free MDA:JX-10 synth from http://mda-vst.com
Step 2: Load it into Renoise and select the “Gangsta Whine” preset
Step 3: Have fun 
Here’s a little something I cooked up earlier for someone else who was asking about the same sound, but used by Eazy E:
http://illformed.org/downloads/eazy-e.mp3
man, i completely forget the name of the synthe dre & suge used a bit!
was it a casio?
Love that sound!
Didn’t Dre and Tupac use that one in California Love as well?