Until taktik update Renoise for high resolutions, I would say that the best option is the one that gives you more space to work, without damaging your eyesight.
It seems that Renoise has strong roots with low resolutions. I’m talking about 15 "laptops or something like that.If you see its distribution on the screen, it fits on a low resolution screen, which will cause many dead spaces if you use a very high resolution monitor (2k or higher). In the latter case, as you have a lot of space, not taking advantage of all the space is not very important.
I would say that, currently, the indeal resolution is the HD (1920x1080) at least. Then, increase the font of the pattern editor and play with the spaces in the preferences. If the menus look too small for you, there is a little trick to increase your fonts a little.
Renoise has a GUI based on pixels, the text boxes are fixed, they are not adaptable. A good example to compare this is Ableton 10. Your vector GUI is a good example of what Renoise could be. I just hope that the fact of making tools is not a burden for Renoise to continue evolving.
But in your case, I would say that the problem is not Renoise 3, but your screen is too small (resolution too low). And I’ve always thought that to make the most of Renoise, the higher the resolution (the height dimension), the better the monitor (at least 2K). Hopefully Taktik is working on this. We know absolutely nothing about his recent plans.
Regarding the VSTi, I have seen some even adaptable in various sizes (as Spire), but I would say that they are more oriented to HD screens, which seems to be the most widely used and accessible resolution for all.If your screen is less than 1080 high, you may have problems with many VSTi, which will go out of the screen.It will depend a lot on the VSTi you use, if they are very old or recent. For example, if you use Kontakt Player, I recommend an HD resolution…
I use two HD (2x 1920x1080) screens with a tower type PC.I use two HD screens with a tower type PC. I have a laptop to test with Renoise (especially when I build tools), but I feel a bit clumsy precisely because I have a little work space.
Make a reflection. Compare the height of 800, 1080, 1440 pixels, or more…Maybe for you a 27" HD screen (1920x1080) would be fine.With the same resolution you will see things somewhat larger compared to a 24" screen.The worst would be to use a very high resolution on small screens. This does not make sense to me.