Can you give more information, less panic please?
Thousands of users use ASIO4ALL and the effects just “disappearing” but the rest of the application working fine seems a bit odd.
“Doesn’t work” isn’t much to go on…
What soundcard? What version of Windows? What specific effects? Renoise effects or just VST effects? A screenshot? An example XRNS?
Links that may of help?
https://forum.renoise.com/t/creamware-pulsar-vsts-asio-settings/25147
http://tutorials.renoise.com/Renoise/SettingUpAudioHardware