Yeah of course. You can mix and match things pretty much however you want, as long as you understand what’s going on and how to get the results you’re looking for. In cases where you’re working with a lot of triplet notes, for example, it can just be a lot easier if your pattern is structured a certain way, otherwise you will probably need to use the note delay command a hell of a lot.
This reminds me of another thread from December where time signatures were discussed a little bit. I posted some examples showing how to alternate between 3/4 and 4/4 time in a song, comparing the LPB method vs the note delay method. You can check that out and see which one feels more comfortable to you, since it really is just a personal preference.