i make some pretty okay music on linux. i’m satisfied with a standard set of ladspa plugs (swh, cmt, tap, caps/c*, foo, invada), little sprinkle of dssi (calf), and a few vsts (loomer aspect and resound, have the TAL stuff but don’t really use it). would love to use the linuxdsp stuff but i’ll need either 64bit VSTs (which the fellow doesn’t provide yet) or LV2 support in renoise. i have a few hardware synths (novation a-station, shruthi-1) that i use from time to time.
i use arch linux, it’s very nice. i only use jack on my systems and avoid pulseaudio whenever possible (because it’s useless and terrible). when i can’t avoid pulseaudio, i use the jack source and sink modules.
i am a nerd and a programmer before i am a musician, and i am very partial to dwm as my window manager, but i understand it’s not for everyone. openbox is nice, xfce is nice, i personally won’t touch the current incarnations of gnome and kde at all.
i have no complaints about my setup. no problems with jack, the ALSA drivers are solid, everything’s fine. i would advise against firewire (ffado is not very good).
in the end, it’s all about how much time and effort you want to spend on your setup. it’s no secret that linux requires much more effort for professional (or amateur) media production than OSX or win32/64. though i’m sure i could have produced more music in a shorter time if i had brought myself up on windows or osx instead of linux, the journey that i have taken over the past 8ish years has done a lot to shape my sound. i started with nothing but midi sequencers and alpha-quality modular synths (beast/bse), moving on to csound (which was a multi-year eye-opening experience for me), energyXT (awful), and finally renoise, which i’ve been using for the past 3 or 4ish years.
i view the relative lack of software as being a benefit, as it has forced me to learn my tools thoroughly. in the case of csound and beast, there was certainly room for me to explore further, as they’re very deep environments. my current workflow is satisfactory to me, i know my tools fairly well. aspect in particular is a very powerful synth, and renoise is likewise a very powerful host. there is plenty of room to explore and learn the tools if you don’t get too caught up in the “oh my god there’s so few things to use!!!” mentality.
2¢.