Maybe it could be done™. But complicated to set up.
I’ve already used manual pitching via pitch modulation to make constant time glides via formula devices for a monophonic instrument. The normal sampler pitching was completely disabled for this, only pitch modulation was used to pitch the sample. It worked very well! I could imagine the fomula device that calcs/interpolates the pitch offset could as well have tuning data inside and adjust the glides and targets accordingly.
Only problem I see is…you most probably have a multisample instrument, and want the multi (per note) samples be preserved, not just use a single one instead. I would need to make a test to see how renoise behaves around that fact. Glide would never trigger new samples just repitch the currently playing, as it does with the standard renoise glides. But I guess it would be of benefit when an adequate sample is triggered from a list on new (non glide) notes.
If you have interest, upload your instrument or a similar, and the tuning file and maybe info about the scale to be used and range of glides and glide behaviour you wish. I will try to see how I can fix it up!