I have Dsi Mopho desktop version and i used VSti plugin
I have a problem with plugin in the Renoise.
After add plugin to instrument i can’t choose preset in the my Mopho, Mopho have crashed preset to empty mode. But if select preset in the plugin i don’t have a problem.
There are some issues with Renoise in the newer OSX environments. Your OSX version is lower though (and you have a VST problem which is actually not a real problem on the new OSX versions), it is a far guess…