Here another post by Urs (maybe outdated since they seem to have sorted out these kind of problems): https://www.kvraudio.com/forum/viewtopic.php?p=7966642#p7966642
This might be an interesting read, too: Developing a fast and responsive GUI - is JUCE too bloated? - Page 2 - DSP and Plug-in Development Forum - KVR Audio
Interestingly, I recently bought a Mac Book Air M1 (Big Sur) and there are no graphics issues on this system when running Renoise, whereas on my iMac (Catalina) I still have to switch to RGB color mode every time I load Renoise, otherwise everything is sluggish as previously described.
So, at least on these latest macs, it appears to be a non-issue.
Nice. Is it also different, if you update your iMac to Bug Sur then? I wonder if Rosetta2 is fixing it, or the system itselfā¦
I updated my iMac Pro (2017) to Big Sur and I still have to change color profiles, unfortunately. I did not do a complete reinstall, though.
I hope this gets addressed for real.
Itās incredibly annoying have to open my OS settings and change the color profile every time I want to use Renoise, then change it back afterward.
As stated previously on my new Macbook Air M1, this isnāt necessary (for whatever reason). But I do most of my music making on my iMac / Catalina.
Agreed, itās very annoying. I made a little script that changes the color profile with the MacOS utility āAlfredā but even that only saves a bit of time and the color profile that works is noticeably harder on the eyes (for me, at least)
Question for you Michael ā can you confirm the UI issues still are not an issue on your newer M1 laptop?
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Correct, on my Mac Book Air M1 the issue does not exist, and I do not have to do any color profile switching. Itās only on my older iMac / Catalina that I encounter the issue.
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Iām running into the same issue on one of the new M1 Macbook Pros, I have to switch to a display preset that uses the Rec 709 color gamut rather than P3 for the UI to be performant. I hope this gets fixed asap as using a non-default mode now seems to break other display features like night shift and the ability to change brightness at all.
The master volume meter also goes ābehindā the bezel in full screen mode, Iām not sure if thereās a way to force the full screen view to not take up the full screen height.
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If you Get Info on an app, thereās an option to āScale to fit below built-in cameraā as a compatibility workaround. The whole screen will shrink just enough to fit below the notch.
Rejoice everybody, the new 3.4 update fixes this issue ā itās no longer necessary to change your Display settings on mac every time you want to use Renoise !! 
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I recently re-installed renoise on a 2018 macbook pro running 10.15 catalina, and experienced a gui lag of >1 second. Literally unusable. Changing colour profiles didnāt help, but turning off metal rendering did. I donāt know if this works better in newer macos versions?